Glucuronyl Transferase Deficiency, Crigler-Najjar Type I treatment in Puebla

It is worth keeping in mind when to seek care: in the case of intense and persistent jaundice in a newborn or infant, early evaluation is key. Crigler-Najjar syndrome type I is a rare inherited disorder in which the liver cannot properly process bilirubin because of the absence of an enzyme, which causes it to build up in the blood.

Why it happens: It is of genetic origin; the lack of the enzyme glucuronyl transferase prevents bilirubin from being eliminated normally.

What may be observed: A marked yellowish color in the skin and eyes from the first days of life, which does not go away like a common jaundice.

Specialists who treat it: The pediatrician and the gastroenterologist are the ones who study and follow up on this condition. If the yellowish coloring is intense or lasts a long time, the prudent thing is to promptly seek a specialized evaluation.